Luisa Amélia Guimarães e Melo, the wife of Portuguese politician and diplomat, Antonio Guterres, died of cancer in 1998 at age 51.

In 1972, Guterres married Luisa, who was then a child psychiatrist. They both had two children, Pedro Guimarães e Melo Guterres (born 1977) and Mariana Guimarães e Melo de Oliveira Guterres (born 1985).

Luisa was confirmed dead at the Royal Free Hospital and was laid to rest at Alto de Sao Joao Cemetery in Lisbon.

Fast forward to 2001, Guterres married Catarina Marques de Almeida Vaz Pinto (b. 1960), a former Portuguese State Secretary for Culture and Culture Secretary for the City Council of Lisbon.

In addition to his native Portuguese, Guterres speaks English, French, and Spanish.

Guterres is a practicing Catholic. During his university years, he joined the Group of Light, a club for young Catholics, where he met Father Vítor Melícias, a prominent Franciscan priest and church administrator who remains a close friend and confidant.